San Francisco 49ers vs. Seattle Seahawks 101024-Free Pick, TNF


San Francisco 49ers vs. Seattle Seahawks 10/10/2024 Free Pick & NFL Betting Prediction


Free NFL Week 6 Pick: 49ers vs. Seahawks Odds

Looking for San Francisco 49ers vs. Seattle Seahawks free NFL picks & NFL odds? NFL betting sees the 49ers taking on the Seahawks on Thursday, October 10th at the Lumen Field. Cappers Picks provides complimentary NFL Football handicapping picks all NFL season long including all NFL Week 6 games so stay tuned for more FREE NFL predictions like this San Francisco Seattle Amazon Prime – Thursday Night Football matchup.

NFL Handicapping Analysis: Week 6

Amazon Prime – Thursday Night Football
(2-3) San Francisco 49ers vs. Seattle Seahawks (3-2)
Date: Thursday, October 10th
Time: 8:15 ET
Venue: Lumen Field, Seattle WA
NFL ATS Betting Lines: (BET NOW!) San Francisco -3.5 | Seattle +3.5
NFL Moneyline Odds: San Francisco -180 | Seattle +152
NFL Betting Total: O/U 47.5

Get ready for a Thursday night showdown that’s sure to be a wild ride as the Seahawks and 49ers clash under the lights in Week 6! Seattle’s trying to bounce back after dropping two straight following a hot 3-0 start, while San Francisco desperately needs a spark to turn around what’s been a lackluster campaign.

With the all-time head-to-head leaning 30-22 in favor of Seattle, these NFC West rivals always bring the heat.

The 49ers won both of their matchups against the Seahawks last year, with a 31-13 victory in the first game and a 28-16 win in the second. In the first game, the 49ers were -7 point favorites, and they were -14.5 point favorites in the second game.

The over/under line for game one was 43 points, and the teams combined for 44 points.

In the second game, the line was 44.5 points.

San Francisco 49ers

After snapping a two-game losing streak with a week 4 win over the Patriots, the 49ers couldn’t keep their momentum going, falling 24-23 to the Cardinals in week 5. San Francisco was a 7-point favorite at home, but the loss dropped their record to 2-3. They are now 0-2 in division games and 0-2 on the road this season.

Despite their sub-.500 record, the 49ers rank 4th in our NFL power rankings and have a 50.7% chance of making the playoffs. They have been favored in all of their games so far and are 2-3 ATS, with an average scoring margin of +4 points per game. Their O/U record is 3-2, with an average of 46.4 points scored in their games.

San Francisco 49ers Stats

Despite a fast start in week 5, scoring 23 points in the first half, the 49ers were shut out in the second half of their 24-23 loss to the Cardinals. Brock Purdy threw for 244 yards, completing 19 of 35 passes, with one touchdown and two interceptions. Jordan Mason led the team in rushing with 89 yards on 14 carries, while Brandon Aiyuk had 8 receptions for 147 yards.

San Francisco ranks 9th in the NFL in scoring, averaging 25.2 points per game, and they are 2nd in the league in total yards per game with 407.4. They are 4th in passing yards per game (263.4) and 7th in rushing yards per game (144). The 49ers have struggled in the red zone, ranking 22nd in the NFL with a conversion rate of 27.3%.

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In the 49ers’ 24-23 loss to the Cardinals, their defense allowed 358 yards and struggled against the run, giving up 169 yards on just 26 attempts (6.5 per attempt). Despite this, they did a good job against the pass, allowing only 189 yards and holding Arizona to a 63.3% completion rate.

San Francisco’s defense forced one interception and limited the Cardinals to a 30% third-down conversion rate. However, they managed just one sack and had a negative quarterback hit differential.

Seattle Seahawks

Despite a two-game losing streak, the Seahawks remain atop the NFC West with a 3-2 record. After a 21-point win over the Dolphins in week 3, Seattle dropped their next two games, including a 29-20 home loss to the Giants in week 5. The Seahawks were 7-point favorites in that matchup but couldn’t get the win, bringing their conference record to 0-2.

Seattle currently has a 28.1% chance of making the playoffs and a 21.6% chance of winning the NFC West. They rank 23rd in our NFL power rankings. Against the spread, the Seahawks are 1-3-1, and their O/U record is 4-1, with the over hitting in two straight games.

Seattle Seahawks Stats

Heading into week 6, the Seahawks rank 20th in our offensive power rankings. They lead the NFL in passing attempts per game (39.8), resulting in 270.8 passing yards per game, which ranks 3rd. Geno Smith threw for 284 yards (28/40) and a touchdown in week 5, after his 395-yard performance in week 4. Seattle ranks 16th in 3rd-down conversions but has been strong in the red zone, converting 72.7% of their trips, which ranks 7th in the league.

On the ground, the Seahawks rank 28th in rushing attempts and 22nd in rushing yards per game, averaging 105.4 yards. Smith led the team with 72 rushing yards in week 5. Kenneth Walker III had 80 yards and 3 touchdowns in week 4, while Zach Charbonnet had 91 yards in week 3. Seattle ranks 10th in red zone attempts and 7th in 1st-quarter scoring.

In their most recent game, the Seahawks’ defense gave up 175 rushing yards on 34 attempts to the Giants. Overall, they allowed 420 yards and 29 points in a 29-20 loss. The Giants had success through the air as well, with Seattle giving up 245 passing yards on 23 completions, including two passing touchdowns. Seattle’s defense did manage to sack the quarterback three times, but they allowed the Giants to convert on 43.8% of their third down attempts.

The Seahawks also allowed the Giants to average 7.2 yards per pass attempt and 67.6% of their passes. Additionally, Seattle’s defense lost the battle in the trenches, finishing with a -4 in the tackles for loss differential.

San Francisco 49ers vs. Seattle Seahawks NFL Football Betting Trends

  • The 49ers are 2-3 in their last five games as a favorite.
  • Conversely, the Seahawks are 3-2 ATS in their last five games as an underdog.
  • Also, the 49ers are 5-5 ATS in their last ten road games.
  • On the other side, the Seahawks have gone 4-4-2 across their last ten home games.
  • Over the 49ers’ last 3 road games, the over/under record is 1-1-1.
  • The Seahawks’ have an over/under record of 2-1 in their last 3 games at home.

49ers vs. Seahawks Line Movement

Open-ML Live-ML Open-Spread Live-Spread
49ers -192 -180 -4 -3.5
Seahawks +160 +152 +4 +3.5

4* Free Week 6 NFL Betting Prediction: San Francisco -3.5

Now, let’s talk betting! The 49ers are favored at -3.5, but that line feels tricky. While I’m not sold on picking a side just yet, the over/under at 47.5? That’s where the money’s at. We’ve got these two offenses combining for a high-scoring affair, blowing past that total.

San Fran has hit the over in 5 of their last 7, and Seattle’s been seeing points fly at home. The 49ers are in a must-win spot, and with their backs against the wall, expect them to come out swinging against a Seahawks team that struggled to put away the Giants last week.

For this week six matchup between the 49ers and Seahawks, we have the 49ers coming out on top by a score of 33-28. With the point spread sitting at -3.5 in favor of the 49ers, we like them to not only win but cover as road favorites.

As for the over/under, with the line at 47.5 points, we have these teams combining for 61 points, making the over our top pick for this matchup.

Buckle up for fireworks—and take the over!

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About Nicolas Basran

New to Cappers Picks, Bazy is looking to take the sports betting world by storm. He’s not here to mess around and want’s to be the Bret Hart of handicapping. You’ll see picks on the usual Big 4 and college games but also the occasional pick from off the beaten path. To paraphrase the Godfather, “Picking ain’t easy” but that’s why Bazy is here, to do the work for you. He’s a die-hard sports fan who takes pride in what he picks but just like Macho Man Randy Savage, Bazy believes the cream will rise to the top.





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